Zhe Monica Zhong

PhD in Bioengineering and Mechanical Engineering, Georgia Tech

Engineering Human Immune Organoids for Translational Immunology

I develop immune organoid and organ-on-chip platforms to decode B-cell and T-cell responses in health and disease, with applications in vaccine and therapeutic response prediction.

Professional portrait of Zhe Monica Zhong

I am Zhe Monica Zhong, a PhD researcher in bioengineering and mechanical engineering focused on human immune organoids, biomaterials, and translational immunology. My work bridges engineered human tissue platforms with clinically relevant immune response prediction.

Organ-on-chip device with microfluidic channels

Organ-on-Chip Models

Integrated tissue models for coordinated local and systemic immune crosstalk.

Immune organoid fluorescence micrograph

Immune Organoid Engineering

Synthetic and human-derived systems for studying adaptive immune function.

Biomaterials and microenvironment image

Biomaterials and Microenvironments

Hydrogel and photopatterned tissue platforms for controlled immune signaling.

Translational research imaging

Translational Research

Preclinical human-model systems for diagnostics and therapeutic decision support.

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Publications
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Patents Filed
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Conference Talks
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Mentees Guided
2023
Nature Materials and ACS Central Science publications on synthetic immune organoid platforms.
2024
Recognition through GT NEXT and Society for Biomaterials awards for translational immunoengineering research.
2025
Human immune organoid work published in Nature Materials with expanded clinical relevance.

I completed my PhD at Georgia Tech, where I worked in the Singh Lab on immune tissue engineering and translational immunoengineering. My research integrates biomaterials, cell engineering, and high-dimensional immune profiling to advance predictive human immune models.

selected publications

  1. Human Immune Organoids to Decode B Cell Response in Healthy Donors and Lymphoma Patients
    Z. Zhong, M. Q. Perez, Z. Dai, and 28 more authors
    Nature Materials, 2025
  2. Combinatorial Targeting of Aberrant Signaling Pathways in Lymphomas Rescues Lymphoid Tumor Microenvironment-mediated Attenuation of MALT1 Inhibitors
    S. B. Shah, C. R. Carlson, K. Lai, and 27 more authors
    Nature Materials, 2023